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mciZ [2017-10-26 14:21:26]
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mciZ [2017-10-26 14:21:26]

FtsZ inhibition peptide
locus
BSU23616
pI
0.00
mw
4.00 kDa
function
inhibits GTPase activity of FtsZ and Z ring formation during sporulation
product
FtsZ inhibition peptide
essential
no
synonyms
S896
Outlinks
KEGGBsubCycUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.8|Cell division] → [category|SW 1.1.8.2|Other genes]
  • [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.5|Newly identified sporulation proteins (based on transcription profiling)]

    • Gene

    Coordinates
    2,459,114 → 2,459,288

    The protein

    Catalyzed reaction/ biological activity

  • inhibits GTPase activity of [protein|41872E2EF00C79918DD077F2EF78F37E24FEB110|FtsZ]and Z ring formation during [SW|sporulation]

    • Structure

  • [PDB|2MRW] [Pubmed|25848052]
  • [PDB|4U39] (the [protein|08EBBA57B807F8C27C37BEB275DF5E206935C698|MciZ]-[protein|41872E2EF00C79918DD077F2EF78F37E24FEB110|FtsZ] complex) [Pubmed|25848052]

    • [SW|Interactions]

  • [protein|08EBBA57B807F8C27C37BEB275DF5E206935C698|MciZ]-[protein|41872E2EF00C79918DD077F2EF78F37E24FEB110|FtsZ] [Pubmed|18284588], KD 150 nM [Pubmed|25848052]

    • References

    Reviews

  • 19680248

    • Original publications

  • 18284588,25848052,23237472,27752253